Medical research has been revolutionized by high-throughput technologies enabling possibilities to analyze the interactions and functions of biological information entities in various ”-ome” layers or clusters of life (http://omics.org/). By combining multiple ”omes”, such as genome, transcriptome, methylome, metabolome, proteome and microbiome, scientists can find novel associations between biological entities, pinpoint relevant biomarkers, and understand the roots of complex diseases. However, the myriad of technologies, approaches and available tools tends to overwhelm researchers new to the field. With this webinar ”Multi-omics methods for studying metabolic disorders: research excellence, wet lab techniques and bioinformatics approaches” we aim to inspire new multi-omics studies and provide guidance to interested researchers, students and other potential collaborators.
The seminar includes lectures from scientists of INTEGROMED consortium: Weizmann Institute of Science (Israel), University of Dundee (United Kingdom), Lund University (Sweden), Latvian Biomedical Research and Study centre (Latvia) and expert in metabolomics from Riga Technical University.
This seminar is aimed at biomedical, molecular biology and bioinformatics students and scientists who are currently doing or planning to do multi-omics studies. Participants don’t need any prior experience.
Webinar is free of charge, times in agenda are Eastern European Time.
Application is mandatory. If you consider to listen only specific lectures, you can still aplly to receive the link to the online seminar and receive record after event.
Preliminary agenda
Date: 29th & 30th November, 2021
Application: open
Application deadline: 25th November
Participation: open application, applicants will receive ZOOM link three days before webinar
Contact: Laura Ansone laura.ansone[at]biomed.lu.lv
Agenda
November 29 | Personalized approaches in metabolic disorders, sneak-peak in multi-omics in laboratory |
Lecturer, organization |
10:00-10:30 | Pharmacogenomics in diabetes mellitus | Prof. Ewan Pearson University of Dundee |
10:30-11:00 | Personalized nutrition based on the gut microbiome | Prof. Eran Segal, Weizmann Institute of Science |
11:00-11:30 | Epigenetics in Human Obesity and Type 2 Diabetes | Prof. Charlotte Ling, Lund University |
11:30-12:00 | The interplay between multiple determinants influencing Type 2 Diabetes therapy efficacy |
Prof. Jānis Kloviņš, Latvian Biomedical Research and Study Centre |
12:00-13:00 | Lunch break | |
13:00-14:00 | Study design, sample collection and processing in microbiome studies | Dr.biol. Ilze Elbere, Latvian Biomedical Research and Study Centre |
14:00-15:00 | NGS methods, challenges, and applications | Alise Jakovele, Latvian Biomedical Research and Study Centre |
15:00-16:00 | DNA-seq library preparation workflow video | |
November 30 | Bioinformatics for different omics | Lecturer, organization |
10:00-11:00 | Introduction in bioinformatics and NGS data processing | Rihards Saksis, Latvian Biomedical Research and Study Centre |
11:00-12:30 | Workshop: basics in command line handling with examples on NGS data analysis (login for HPC server with SSH protocol will be ensured) | Rihards Saksis, Latvian Biomedical Research and Study Centre |
12:30-13:30 | Lunch break | |
13:30-14:30 | Metagenome data analysis, approach for analyzing within-species variation in the microbiome | Liron Zahavi, Weizmann Institute of Science |
14:30-15:30 | DNA methylation data analysis, basics of different approaches, challenges | Dr. Alexander Perfilyev, Lund University |
15:30-16:30 | From sample preparation to LC-MS to data in metabolomics: the devil is in the details | Dr. chem. Kristaps Kļaviņš, Riga Technical University |